Association of the GDNF gene with depression and heroin dependence,but not schizophrenia,in a Chinese population |
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| Authors: | Xian-cang Ma Ce Chen Feng Zhu Wei Jia Cheng-ge Gao |
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| Affiliation: | 1. Department of Psychiatry, The First Affiliated Hospital of Xi''an Jiaotong University College of Medicine, Xi''an, Shaanxi, China;2. Center for Translational Medicine, The First Affiliated Hospital of Xi''an Jiaotong University College of Medicine, Xi''an, Shaanxi, China;3. Methadone Maintenance Treatment Clinic, Xi''an Mental Health Center, Xi''an, Shaanxi, China |
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| Abstract: | The association of seven GDNF tag SNPs with depression, heroin dependence (HD) and schizophrenia was evaluated in Chinese. An increased risk of HD and depression was associated with rs2910709 T/T genotype and rs884344 C allele, respectively, suggesting GDNF is a novel susceptibility gene for depression and HD. |
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| Keywords: | Depression Heroin Glial cell line-derived neurotrophic factor |
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