| 江苏省新甲型H1N1流感疫苗免疫后抗体水平变化趋势研究 |
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| 引用本文： | 秦圆方,祁贤,李亮,祖荣强,吴斌,付建光,王慎骄,田华,嵇红,霍翔,汤奋扬,朱凤才,汪华. 江苏省新甲型H1N1流感疫苗免疫后抗体水平变化趋势研究[J]. 疾病控制杂志, 2011, 15(9): 773-776 |
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| 作者姓名： | 秦圆方 祁贤 李亮 祖荣强 吴斌 付建光 王慎骄 田华 嵇红 霍翔 汤奋扬 朱凤才 汪华 |
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| 作者单位： | 江苏省疾病预防控制中心,江苏,南京,210009 |
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| 摘 要： | 目的了解新甲型H1N1流感疫苗免疫前后人群抗体水平动态变化情况。方法随机选取部分疫苗接种人群为受试者,微量半加敏血凝抑制实验检测免疫前、免疫后1个月与免疫后3个月的血清抗体水平,计算抗体阳性率与抗体几何平均滴度(GMT),并进行统计学分析。结果免疫前、免疫后1个月与3个月抗体阳性率分别为13.64%(9.58%~18.61%)、83.63%(78.15%~88.20%)、77.06%(71.09%~82.32%),GMT分别为9.36(8.30~10.56)、122.53(100.29~149.70)、96.07(77.85~118.54)。免疫前与免疫后1个月、3个月后相比,抗体阳性率与GMT差异均有统计学意义。免疫后1个月与免疫后3个月两者差异均无统计学意义。结论本研究所用甲型H1N1流感病毒裂解疫苗免疫后抗体水平明显升高,且维持时间较长。
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| 关 键 词： | 流感病毒A型 H1N1亚型 流感疫苗 抗体 |
Study on tendency of antibodies levels of influenza A(H1N1) vaccine inoculated population in Jiangsu Province |
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| QIN Yuan-fang,QI Xian,LI Liang,ZU Rong-qiang,WU Bin,FU Jian-guang,WANG Shen-Jiao,TIAN Hua,JI Hong,HUO Xiang,TANG Fen-yang,ZHU Feng-cai,WANG Hua. Study on tendency of antibodies levels of influenza A(H1N1) vaccine inoculated population in Jiangsu Province[J]. Chinese Journal of Disease Control and Prevention, 2011, 15(9): 773-776 |
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| Authors: | QIN Yuan-fang QI Xian LI Liang ZU Rong-qiang WU Bin FU Jian-guang WANG Shen-Jiao TIAN Hua JI Hong HUO Xiang TANG Fen-yang ZHU Feng-cai WANG Hua |
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| Affiliation: | QIN Yuan-fang,QI Xian,LI Liang,ZU Rong-qiang,WU Bin,FU Jian-guang,WANG Shen-Jiao,TIAN Hua,JI Hong,HUO Xiang,TANG Fen-yang,ZHU Feng-cai,WANG Hua.Jiangsu Center for Disease Control and Prevention,Nanjing 210009,China |
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| Abstract: | Objective To investigate the developing tendency of antibodies levels of the type A(H1N1) influenza vaccine inoculated people.Methods Observation objects were randomly selected from people vaccinated with influenza A(H1N1) vaccine,and their antibody titers were tested with Hemagglutination inhibition(HI) assays before immunization,1 month and 3 month after it respectively.Antibody positive rates of influenza A(H1N1) virus and their Geometric mean titer(GMT) of HI antibody were estimated.Results The seroposi... |
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| Keywords: | Influenza A virus H1N1 subtype Influenza vaccines Antibodies |
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