无症状性脑梗死患者首发症状性急性脑卒中的临床特征及相关危险因素

目的:分析无症状性脑梗死(silent cerebral infarction,SCI)患者首发症状性急性脑卒中的临床特征及危险因素。方法:186例急性脑卒中患者,其中50例合并SCI,纳入SCI组,其余136例未合SCI,纳入非SCI组,对两组研究对象的临床资料进行Logistic回归分析。结果:合并SCI的首发症状急性脑梗死患者病情重,梗死面积大,预后较差;高龄、高血压、糖尿病、高血脂症、高同型半胱氨酸血症及缺血性心脏病是SCI发病的相关因素(P<0.05),其中高血压、高同型半胱氨酸血症、缺血性心脏病为独立危险因素。结论:合并SCI的首发症状急性脑梗死患者病情重,梗死面积大,预后较差,疾病进展受多重因素的影响,临床医师应充分重视。

Clinical features and risk factors of acute symptomatic stroke in patients with silent cerebral infarction

Objective:To analyze clinical features and risk factors of acute symptomatic stroke in patients with silent cerebral infarction(SCI).Methods:In the cases of 186 patients with acute symptomatic stroke,50 patients with SCI were included in the SCI group;other 136 patients not associated with SCI were included in the non SCI group.The clinical subjects of the two groups were given Logistic regression analysis.Results:Patients with SCI presented with severe illness,large infarct size,and the prognosis was not very satisfactory.Age,hypertension,diabetes,hyperlipidemia,high homocysteine,ischemic heart disease were the relevant factors in the pathogenesis of SCI (P<0.05).And the hypertension,high homocysteine and ischemic heart disease were the independent risk factors.Conclusion:Acute symptomatic stroke patients with SCI presented with severe illness,large infarct size,and the prognosis was not very satisfactory.The progress of disease was influenced by many factors,and clinicians should pay adequate attention.