The role of polyglycolic acid rods in the regeneration of cartilage from perichondrium in rabbits. |
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| Authors: | M M Ruuskanen M J Kallioinen O I Kaarela J A Laiho P O T?rm?l? T J Waris |
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| Affiliation: | Department of Surgery, Oulu University Central Hospital, Finland. |
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| Abstract: | The role of polyglycolic acid (PGA) rods in the regeneration of cartilage from perichondrium was investigated in 12 growing rabbits. The fifth rib cartilage was resected subperichondrially from both sides. A 10 X 1.5 mm self-reinforced polyglycolic acid (SR-PGA) rod was inserted on one side to replace the resected cartilage and the retained perichondrium was sutured around the implant. On the control side the perichondrium was shaped into a tube without an implant. Samples were taken 4, 12, and 20 weeks after operation. Pronounced neocartilage formation was seen on both sides, and had grown to form a tube around the implant. Also new bone formation was seen in 12 and 20 weeks. Foreign body reaction was seen inside the implants in every animal. |
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