| 补肾活血饮治疗原发性帕金森病的疗效观察 |
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| 引用本文： | 李军艳,杨明会,窦永起,刘毅,李敏. 补肾活血饮治疗原发性帕金森病的疗效观察[J]. 解放军医学杂志, 2011, 36(3): 273-276 |
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| 作者姓名： | 李军艳 杨明会 窦永起 刘毅 李敏 |
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| 作者单位： | 1. 济南军区青岛第一疗养院,山东青岛,266071
2. 解放军总医院中医研究所,北京,100853 |
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| 基金项目： | “十一五”国家科技支撑计划重大项目资助课题(2006BAI04A11-1) |
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| 摘 要： | 目的观察中药补肾活血饮配合西药治疗帕金森病(PD)的临床疗效。方法采用随机对照试验,纳入PD患者100例,剔除5例、脱落4例,完成研究者共91例。其中治疗组(中药+西药组)47例,对照组(西药组)44例,疗程3个月。采用统一帕金森病评定量表(UPDRS)评分、H-Y分级的变化来评价治疗的有效率、运动功能的改善情况等。结果治疗组有效率44.68%,疗效优于对照组(11.36%,P<0.05)。治疗组治疗后各时间点UPDRS总分较对照组下降明显(P<0.05)。治疗组各时间点UPDRSⅡ评分与治疗前相比明显降低(P<0.01),对照组仅治疗后1个月较治疗前降低(P<0.05);与对照组比较,治疗后2、3个月时治疗组UP-DRSⅡ评分下降更为明显(P<0.05)。治疗组各时点UPDRSⅢ评分与治疗前相比明显降低(P<0.01),对照组在治疗后1、3个月较治疗前降低(P<0.05)。两组间UPDRSⅢ评分、H-Y分级变化差异无统计学意义(P>0.05)。结论补肾活血饮具有增效减毒作用,与西药联合应用在改善PD患者的运动功能和日常生活能力方面优于单用西药。
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| 关 键 词： | 帕金森病 补肾活血饮 中西医结合疗法 治疗,临床研究性 |
Clinical effect of "BUSHEN HUOXUE YIN" on patients with Parkinson's disease |
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| LI Jun-yan,YANG Ming-hui,Dou Yong-qi,LIU Yi,LI Min. Clinical effect of "BUSHEN HUOXUE YIN" on patients with Parkinson's disease[J]. Medical Journal of Chinese People's Liberation Army, 2011, 36(3): 273-276 |
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| Authors: | LI Jun-yan YANG Ming-hui Dou Yong-qi LIU Yi LI Min |
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| Affiliation: | LI Jun-yan,YANG Ming-hui,Dou Yong-qi,LIU Yi,LI Min.Qingdao First Sanatorium of Jinan Military Command,Qingdao,Shandong 266071,China |
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| Abstract: | Objective To investigate the clinical effect of BUSHEN HUOXUE YIN(BHY,a Chinese traditional medicine) combined with western medicine on patients with Parkinson's disease(PD).Methods One hundred PD patients were enrolled in the randomized control trial(RCT).The patients were randomly divided into two groups(50 each): treatment group(BHY and western medicine,peros) and control group(western medicine only,peros).At the end of the 3rd month,47 patients in treated group and 44 patients in control group completed... |
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| Keywords: | Parkinson's disease BUSHEN HUOXUE YIN therapy integration of Chinese and Western medicine investigational |
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