| 内毒素增敏系统与严重烧伤脓毒症的关系及其临床意义 |
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| 引用本文： | 董宁,姚咏明,于燕,曹玉珏,贺立新,盛志勇.内毒素增敏系统与严重烧伤脓毒症的关系及其临床意义[J].解放军医学杂志,2011,36(1):21-23. |
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| 作者姓名： | 董宁 姚咏明 于燕 曹玉珏 贺立新 盛志勇 |
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| 作者单位： | 1. 解放军总医院第一附属医院全军烧伤研究所,北京,100048
2. 北京佑安医院烧伤科,北京,100054 |
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| 基金项目： | 国家重点基础研究发展计划(2005CB522602); 国家自然科学基金(30872683); 首都医学发展基金重点项目(2003-2023) |
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| 摘 要： | 目的 探讨严重烧伤患者内毒素增敏系统--脂多糖结合蛋白/脂多糖受体CD14(LBP/CD14)的变化与严重脓毒症的关系及其临床意义.方法 选择35例烧伤体表总面积大于30%患者,根据烧伤脓毒症的定义和诊断标准分为脓毒症组(19例)和非脓毒症组(16例),应用酶联免疫吸附试验检测患者烧伤后1、3、5、7、14、21、28...
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| 关 键 词： | 烧伤 脂多糖结合蛋白 抗原 CD14 细胞因子类 脓毒症 |
Relationship between sensitization system of endotoxin and severe burn sepsis and its clinical significance |
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| DONG Ning,YAO Yong-ming,YU Yan,CAO Yu-jue,HE Li-xin,SHENG Zhi-yong.Relationship between sensitization system of endotoxin and severe burn sepsis and its clinical significance[J].Medical Journal of Chinese People's Liberation Army,2011,36(1):21-23. |
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| Authors: | DONG Ning YAO Yong-ming YU Yan CAO Yu-jue HE Li-xin SHENG Zhi-yong |
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| Institution: | DONG Ning,YAO Yong-ming,YU Yan,CAO Yu-jue,HE Li-xin,SHENG Zhi-yong.Burns Institute,First Hospital Affiliated to General Hospital of PLA,Beijing 100048,China |
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| Abstract: | Objective To explore the relationship between the changes of lipopolysaccharide-binding protein(LBP) and CD14 as a sensitization system of endotoxin and severe burn sepsis,and investigate the clinical significance of the relationship.Methods Thirty-five severe burn patients(>30% TBSA) were involved in present study and divided into sepsis group(n=19) and non-sepsis group(n=16) based on the definition and diagnosis standard of sepsis.The blood samples were collected on day 1,3,5,7,14,21 and 28 after burn and... |
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| Keywords: | burns lipopolysaccharide-binding protein antigens CD14 cytokines sepsis |
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