应用速度向量成像技术评价急性期川崎病患儿左室收缩功能

目的应用速度向量成像技术对急性期川崎病患儿左心收缩功能进行评价，以寻求川崎病患儿早期心脏损害的依据。方法对39例急性期川崎病患儿与40例正常儿童进行超声检查。于胸骨旁左室长轴切面测量各腔室径线；根据STeich法计算左心室射血分数（EF）及缩短分数（FS）；采集心尖四腔、心尖两腔三个完整的心动周期存入光盘，脱机分析。应用VVI技术测量心尖四腔切面室间隔、侧壁及心尖两腔切面下壁、前壁的基底段、中间段和心尖段的收缩期峰值速度（VS）、应变（sys）、应变率（SRS）等指标。比较两组间各参数。结果患儿组EF与正常组相比无统计学差异；患儿组收缩期峰值速度（VS）、收缩期峰值应变率（SRS）低于正常组，在所有基底部和部分中间节段有统计学意义（P〈0．05）。结论急性期川崎病儿童左室长轴方向收缩功能受损。

Assessment of left ventricular systolic function in children with acute Kawasaki disease by velocity vector imaging

Objective By assessing the left ventricular(LV) function in children with acute Kawasaki disease(Kd) through velocity vector imaging,the clues of early heart damage on children with KD may be found.Methods Forty healthy subjects and thirty nine subjects with acute Kawasaki disease are examined by the ultrasonography.The diameters of all ventricles are measured from the axial section of left ventricular by the bosom bone.According to STeich,EF and FS will be calculated.Off-line LV velocity profiles along LV apical two-chamber view and four-chamber view are obtained synchronously.The peak systolic velocity(VS),systolic peak strain and systolic peak strain rate(SRS) were measured from the six walls at basal segment and midwall segment using VVI.All parameters are compared among the two groups.Results The peak strain rate in acute KD group was lower than that in control group significantly at all basal segments and some midwall segments(P < 0.05).Conclusion The left ventricular longitudinal systolic functions in acute Kd children are impaired.