肝硬化患者凝血四项检测结果的分析

目的:检测50例肝硬化患者的血浆凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、纤维蛋白原的含量(FIB),与正常对照进行比较,探讨其临床意义。方法:PT、TT、APTT、FIB含量均采用凝固比浊法进行测定。结果:肝硬化患者PT、APTT、TT较对照组明显延长(P<0.01),FIB含量较对照组明显减少(P<0.01)。结论:肝硬化患者血浆凝血因子异常是加重其疾病发展的原因之一,患者处于低凝状态且纤溶系统受损,所以对肝硬化患者进行凝血四项的检测,可早期发现肝病造成的凝血机制障碍,对肝硬化患者出血的抢救和治疗有重要意义。

Plasma Coagulation Factors in Patients With Cirrhosis

Objective To explore the clinical singnificance. Prothrombin time (PT),thrombin time(TT),activated partial thromboplastin time (APTT),fibrinogen(FIB) were detected in 50 samples of hepatocirrhosis.Methods PT,TT,APTT,FIB were detemined by coagulant turbidity method.Results PT,TT and APTT of the patients group were significantly higher than those of the control group,FIB were significantly lower than those of the control group.Conclusion The PT,TT and APTT interval, the levels of FIB are abnormal in patients with hepatic cirrhosis,The patients with cirrhosis have hypocoagulability.The fibrinolvsis system suffers injury,they are valuable in identifying coagulation disorders,predicting bleeding tendency and estimating prognosis.