社区中老年男性膀胱过度活动症患病率的调查研究

目的 探讨社区中老年男性膀胱过度活动症(OAB)的患病状况以及与年龄、下尿路症状的相关性.方法 2007年5月至2008年6月,随机选择50岁以上北京多个社区男性人群作为研究对象.下尿路症状的评估包括国际前列腺症状评分(IPSS)、生活质量(QOL)评分、腹部B超前列腺体积、残余尿量测定及最大尿流率测定.OAB的评估主要依据患者尿急的状况确定,将IPSS评分表中第4项得分≥2定义为OAB.结果 本研究共调查社区中老年男性人群1656人,符合本研究要求的共计1639人.年龄50～89岁,平均(64±10)岁.OAB的患病率为26.3%(431/1639).OAB的患病率与社区中老年男性的年龄、IPSS评分、QOL评分、前列腺体积、残余尿量以及最大尿流率均具有显著相关性(均P＜0.01).对年龄以及IPSS评分的分层研究发现,OAB的患病率随着年龄的增加以及下尿路症状的加重明显升高(P＜0.01).结论 社区中老年男性OAB的患病率随年龄增长逐渐增加,同时OAB明显影响中老年男性的生活质量.

Prevalence of overactive bladder in a community-based male aging population

Objective To investigate the situation of overactive bladder (OAB) in a communitybased male population. Methods Male participants over 50 years old were randomly selected from multiple communities in Beijing. The evaluation of lower urinary tract symptoms (LUTS) including the International Prostate Symptom Score ( IPSS), quality of life (QOL) score, prostate volume and post voiding residue (PVR) by abdominal ultrasonography, and maximum flow rate (Qmax). Definition of OAB was determined as the score of item number 4 in IPSS ≥2. Results Of 1656 male participants enrolled, a total of 1639 men met our study criteria. The mean age was (64 ± 10) years. The prevalence of OAB was 26. 3% (431/1639), and was significantly related to age, IPSS,QOL score, prostate volume,PVR and Qmax(P ＜0.01).The prevalence of OAB was closely associated with aging ( P ＜ 0. 01 ) and the degree of LUTS(P＜0.01).Conclusions The prevalence of OAB increased with aging of the community-based male population. OAB would obviously affect the quality of life of the aging men.