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不同浓度氯化钠液救治失血性休克患者的临床效果
引用本文:汪卫星,胡四平,吴鹤芬,单汉民,刘洋. 不同浓度氯化钠液救治失血性休克患者的临床效果[J]. 中华医学杂志, 2010, 90(3). DOI: 10.3760/cma.j.issn.0376-2491.2010.03.014
作者姓名:汪卫星  胡四平  吴鹤芬  单汉民  刘洋
作者单位:浙江省湖州市中心医院麻醉科,313000
基金项目:浙江省湖州市科技计划基金 
摘    要:目的 观察使用不同浓度氯化钠液救治失血性休克的临床效果.方法 将75例失血性休克病人按照数字随机法平均分为5组,分别使用0.9%(对照组)、3%、4.5%、6%、7.5%氯化钠液静脉输注并观察患者治疗前后平均动脉压、心率、血气、肾功能、电解质的变化.结果 与0.9%氯化钠相比,给药后其他4组患者平均动脉压均快速回升但仅有4.5%氯化钠液组维持时间可达30min(P<0.05);6%、7.5%氯化钠液治疗后患者血浆K~+下降明显(P<0.05),而4.5%氯化钠液组各项观察指标可以维持适当水平.结论 4.5%氯化钠液用于复苏失血性休克,不仅能快速使血压回升并维持时间较长,同时对机体内环境干扰较小.

关 键 词:氯化钠溶液  高渗  休克  出血性  治疗  临床研究性

The effect of NaCl solution with different concentration on the resuscitation of hemorrhagic shock
WANG Wei-xing,HU Si-ping,WU He-fen,SHAN Han-min,LIU Yang. The effect of NaCl solution with different concentration on the resuscitation of hemorrhagic shock[J]. Zhonghua yi xue za zhi, 2010, 90(3). DOI: 10.3760/cma.j.issn.0376-2491.2010.03.014
Authors:WANG Wei-xing  HU Si-ping  WU He-fen  SHAN Han-min  LIU Yang
Abstract:Objective To observe the clinical results of different concentration NaCl solution in hemorrhagic shock resuscitation. Methods The 75 cases with hemorrhagic shock were divided into five groups by means of random number table. Treat the cases with 0. 9% (control group)、3%、4. 5% 、6% and 7.5% NaCl solution, respectively. Observe the changes of BP,、HR、 blood gas、renal function、electrolyte concentration of plasma, before and after treatment. Results After transfusion, compared with groups of 0. 9% NS, the mean BP of patients in other four groups rise more quickly but only the group of 4. 5% can last 30 minutes (P < 0. 05), and K~+ of plasma in groups of 6% ,7. 5% NS decline more obviously (P < 0. 05) , the group of 4. 5% maintain the best lever. Conclusion The mean BP of patients rise quickly and continue for a long time, in the group of 4. 5%. Meanwhile the internal environment of the body maintain relatively stable in the group of 4. 5%.
Keywords:Sodium chloride solution  hypertonic  Shock  hemorrhagic  Therapies  clinical investigation
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