代谢综合征和冠状动脉粥样硬化的相关性研究

目的探讨代谢综合征(MS)与冠状动脉粥样硬化的关系。方法选择拟诊冠心病的住院患者64例,分为MS组(n=26)和非MS组(n=38)。所有患者经16排多层螺旋CT冠状动脉造影检查,并作心血管危险因素评价。结果MS发生率随病变的冠状动脉数增加而升高(P<0.05)。冠状动脉钙化分数随MS危险因素增加而递增。Logistic回归分析显示MS发生与冠状动脉钙化分数、体质量指数和高密度脂蛋白相关(P<0.05)。MS组患者冠状动脉钙化程度和发生率均高于非MS组(P<0.05)。结论MS与冠状动脉钙化、狭窄之间存在显著相关关系。

Relationship between metabolic syndrome and coronary atherosclerosis

Objective To investigate the relationship between metabolic syndrome(MS) and severity of coronary atherosclerosis. Methods Sixty-four hospitalized patients diagnosed as coronary heart disease were divided into MS group(n=26)and non-MS group(n=38).All the patients underwent 16-row multi-slice CT coronary angiography,and cardiovascular risk factors were evaluated. Results The prevalence of MS increased with the number of stenosed coronary arteries(P<0.05).Coronary artery calcification score increased with the number of MS risk factors.It was revealed by logistic regression analysis that the presence of MS was related with coronary calcification score,body mass index and high density lipoprotein(P<0.05).Comopared with patients without MS,those with MS showed a significant increase in the prevalence of coronary calcification and coronary calcification score(P<0.05). Conclusion MS is significantly associated with the extent of coronary calcification as well as coronary stenosis.