高通量血液透析对血清钙、磷和甲状旁腺素的影响

目的:探讨高通量血液透析对血清钙、磷和甲状旁腺素(PTH)的影响。方法:采用双盲随机对照,A组应用高通量透析,B组应用普通透析,分时点检测病人空腹透析前血清总钙、磷和全段PTH的水平。结果:A组病人血清钙各时点均数在正常范围,相互比较无显著变化(P>0.05);血清磷和血清全段PTH在3个月时显著降低并维持犤血磷(1.98±0.08)mmol/L,血清全段PTH(256.16±101.22)pg/L犦,P<0.05。B组病人血清钙在正常范围,血清磷和血清全段PTH水平较高,各时点均数比较,P>0.05。A组血清磷和PTH在3个月时明显低于B组(P<0.05),之后维持;血清钙两组无差异。结论:高通量透析可增加血磷的清除量,有效降低维持性血液透析患者的血磷和PTH。

Effects of high flux hemodialysis on serum calcium, phosphorus and parathyroid hormone

Objective To explore the effects of high flux hemodialysis on serum calcium(Ca), phosphorus(P) and parathyroid hormone (PTH). Methods Forty one patients with chronic kidney diseases were randomly divided into two groups. Group A used high flux hemodialysis; group B used low flux maintenance hemodialysis. Before eating breakfast and hemodialysis, the serum Ca and P and PTH of the patients were examined on the different times. Results Serum Ca of group A patients was in the normal degree on the different tim...