Reversible cardiomyopathy due to carnitine deficiency from renal tubular wasting |
| |
Authors: | V. R. Zales D. W. Benson Jr. |
| |
Affiliation: | (1) Division of Cardiology, Department of Pediatrics, The Children's Memorial Hospital, 2300 Children's Plaza, 60614 Chicago, IL, USA;(2) Present address: Deborah Heart Institute, 08015 Brown Mills, NJ, USA |
| |
Abstract: | The clinical course of a 4-month-old male infant with a dilated cardiomyopathy secondary to renal tubular losses of carnitine is outlined. He was admitted to the hospital with severe congestive heart failure. An echocardiogram demonstrated normal anatomy. The left ventricular shortening fraction measured 10%. A comprehensive cardiomyopathy evaluation was initiated.The total plasma carnitine level was only 25 mol/ml, but the urine carnitine measured 434 nm/mg of creatinine. He was begun on orall-carnitine and weaned from mechanical ventilation and inotropic support 10 days later. Two years later he remains asymptomatic with normal left ventricular function. |
| |
Keywords: | Carnitine deficiency Cardiomyopathy Renal wasting |
本文献已被 SpringerLink 等数据库收录! |
|