Acute exacerbation of interstitial pneumonia associated with active systemic lupus erythematosus in a patient with rheumatoid arthritis] |
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| Authors: | Ayaka Sadakata Masao Yamaguchi Yoshikata Misaki Akiko Komiya Yasuo To Motoyasu Iikura Hirokazu Yamada Ryoichi Tanaka Makoto Dohi Kazuhiko Yamamoto |
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| Affiliation: | Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan. |
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| Abstract: | A 36-year-old woman with rheumatoid arthritis was admitted to our hospital for evaluation of newly developed active systemic lupus erythematosus (SLE). After hospitalization, she showed progressive respiratory failure. Chest CT revealed exacerbation of interstitial pneumonia, showing acute development of air-space consolidation and ground-glass opacity in addition to intensified reticular shadows. Administration of high-dose corticosteroids and cyclosporine A resulted in recovery from respiratory failure, accompanied by obvious improvement in the chest radiographs and CT, as demonstrated by the disappearance of air-space consolidation and ground-glass opacity. Clinically, the exacerbation of her interstitial pneumonia was compatible with acute lupus pneumonitis, a rare complication with active SLE. |
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