纤维支气管镜治疗支气管扩张并感染临床研究

目的：评价纤维支气管镜肺泡灌洗对支气管扩张并感染的治疗作用和安全性。方法：治疗组48例给予全身抗炎支持治疗,经纤维支气管镜肺泡灌洗及局部注药。对照组48例给予全身抗炎支持治疗并经纤维支气管镜肺泡灌洗。结果：治疗组和对照组咳嗽消失时间分别为（13.6±3.8）d和（14.1±3.9）d,P〉0.05。有效率分别为85.42%和81.25%,P〉0.05。不良反应发生率分别为6.25%和4.17%,P〉0.05。结论：纤维支气管镜灌洗治疗支气管扩张并感染是一种安全、简单、有效的方法,值得在临床推广使用,单纯灌洗和药物保留灌注在疗效和不良反应方面无显著差异。

A clinical observation on bronchiectasis with infection treated with fibrobronchoscope

Objective： To study the effect and safety of bronchoalveolar lavage （BAL） therapy with fibronchoscope for patients with bronchiectasis and infection. Methods. Forty--eight patients in treatment group were treated with general antibiotic and BAL with local medication, and the other 48 patients in control group were treated with general antibiotic and BAL without local medication. Results. The coughduration, effective rate and adverse reaction incidence in treatment and control groups were 13.6±3.8 days vs 14.1±3. 9 days （P〉0.05）, 85.42%0 vs 85.42% （P〉0.05）, and 6.25% vs 4. 17% （P〉0.05） respectively. Conclusion： The BAL therapy with fibronchoscope is safe, simple and effective for bronchiectasis with infection, and there is no obvious differece in efficacy and adverse reactions.