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The relationship between gastric microbiota and gastric disease
Authors:Shuyi Zhang  Dan Shi  Muran Li  Yanru Li  Ximo Wang
Institution:1. Endoscopy Center, Tianjin Union Medical Center, Tianjin, China;2. Tianjin Medical University Graduate School, Tianjin, China;3. Department of gastroenterology, Tianjin Union Medical Center, Tianjin, China;4. Tianjin Clinical Medicine Research Centre for ITCWM Acute abdomen Tianjin Hospital of ITCWM Nankai Hospital, Tianjin, China
Abstract:Traditionally, the stomach was believed to be a sterile organ unsuitable for microbiota growth. However, the discovery of H. pylori subverted this conception. With the development of molecular techniques, an abundance of microbiota of great diversity was found in the stomach. In addition, various lines of evidence suggest that the gastric microbiota plays a critical role in the development and progression of the gastric disease.The gastrointestinal microbiome plays an important role in various physiologic and pathologic processes.
Keywords:Gastric microbiota  Helicobacter pylori  chronic atrophic gastritis  autoimmune gastritis  gastric cancer
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