|
|||||
|
|
| 去脂胶囊对高脂血症性脂肪肝大鼠作用的实验研究 | |
| 引用本文： | 冯明辉,杜发斌,庞杰,赵顺利. 去脂胶囊对高脂血症性脂肪肝大鼠作用的实验研究[J]. 中西医结合肝病杂志, 2006, 16(5): 283-285 |
| 作者姓名： | 冯明辉 杜发斌 庞杰 赵顺利 |
| 作者单位： | 1. 江门市五邑中医院,广东,江门,529000 2. 广东中医药大学2004级博士班 3. 湖南中医学院2003级硕士班 |
| 基金项目： | 广东省中医药管理局科研项目 |
| 摘 要： | 目的：探讨去脂胶囊对高脂血症性脂肪肝大鼠的作用和机制。方法：建立高脂血症性脂肪肝大鼠模型。以高、中、低剂量去脂胶囊进行干预，通过肉眼、血液生化及病理检查，观察其对脂肪肝大鼠的一般情况，肝体比、血脂、肝脂、肝功能、病理改变等的影响。结果：去脂胶囊能明显降低脂肪肝大鼠血脂和减轻肝脂变、肝细胞坏死程度，与对照组比较差异有显著性意义（P〈0．05，P〈0．01）。结论：去脂胶囊对大鼠脂肪肝有肯定治疗作用。 |
| 关 键 词： | 高脂血症 脂肪肝 去脂胶囊/药效学 |
| 收稿时间： | 2006-08-31 |
| 修稿时间： | 2006-08-31 |
Experimental study of the effects of Quzhi Capsule on hyperlipidemia fatty liver in rats. |
|
| FENG Ming-hui, DU Fa-bing, PANG Jie, et al China). Experimental study of the effects of Quzhi Capsule on hyperlipidemia fatty liver in rats.[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2006, 16(5): 283-285 | |
| Authors: | FENG Ming-hui DU Fa-bing PANG Jie et al China) |
| Affiliation: | Department of Internal Medicine of Wuyi Hospital ( Jiangmen Guangdong, 529000 |
| Abstract: | Obiective:To study the therapeutic effect and mechanism of Quzhi Capsule on fatty live in rats. Methods:Fatty liver model of wistar rats was made by feeding high caloric diet.Naked eyes, blood biochemistry and pathological changes were examined to observe the effect of Quzhi Capsule on common conditions, blood lipid level, enzyme, the ratio of liver to body weight and histological change of the fatty liver rats. Results: Quzhi Capsule could lower blood lipid level, lighten the degree of hepatic and hepatocell necrosis of wistar rats. There was signifcant difference as compared with DL-Methionine group (P<0.05or 0.01).Conclusions:Quzhi Capsule group has better effect in the treatment of hyperlipidemia fatty liver in rats. |
| Keywords: | hyperlipidemia fatty liver Quzhi Capsule/pharmacodynamics |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |