米非司酮治疗功能失调性子宫出血的临床研究

目的:观察米非司酮治疗更年期功能失调性子宫出血的临床疗效.方法:选取我院自2006年3月至2010年5月收治的105例更年期功能失调性子宫出血患者按照治疗方法不同分为观察组(米非司酮治疗组)52例和对照组(去氧孕烯雌醇片)53例,比较两组患者的临床疗效.结果:观察组显效32例,有效16例,总有效率为92.3%;对照组显效21例,有效22例,总有效率为81.1%.两组总有效率比较差异显著(P<0.01),具有统计学意义.观察组与对照组治疗后性激素FSH、LH、E2及P水平比较均有显著性差异(P<0.01),具有统计学意义.结论:应用米非司酮治疗更年期功能失调性子宫出血效果理想,值得推广应用.

Clinical Study on the Treatment of Mifepristone on Dysfunctional Uterine Bleeding

Objective: To observe the clinical effect of the treatment of mifepristone on climacteric dysfunctional uterine bleeding.Method: 105 patients with climacteric dysfunctional uterine bleeding treated in our hospital from March 2006 to May 2010 were selected and divided into 2 groups,the observation group(mifepristone treatment group)for 52 cases and the control group(desogestrel estradiol tablets treatment group) for 53 cases,and compared the clinical effects of the patients in 2 groups.Result:(1) As for the observation group,32 cases were significantly effective,16 cases were effectual with a total cure rate as 92.3%.As for the control group,21 cases were significantly effective,22 cases were effectual with a total cure rate as 81.1%.There was significant difference in the total cure rate of the 2 groups(P<0.01),which has statistical difference.(2) There was significant difference in the levels of sex hormone FSH,LH,E2 and P after treatment of the 2 groups(P<0.01),which has statistical difference.Conclusion: The effects of applying mifepristone to treat climacteric dysfunctional uterine bleeding is perfect,which is worthy popularization and application.