小剂量奥曲肽治疗肝硬化顽固性腹水的临床疗效分析

目的:探讨小剂量奥曲肽治疗肝硬化顽固性腹水的方法及疗效.方法:随机抽取本院收治的90例肝硬化顽固性腹水患者,自愿分为两组,对照组42例行常规综合治疗,实验组48例在此基础上加用奥曲肽治疗.随访1-2月,比较两组患者的腹围、尿量、血清尿素氮、血清肌酐及血清白蛋白等生化指标和临床疗效.结果:两组内相比,治疗后患者的各项生化指标均优于治疗前(P<0.05),而实验组患者的各项生化指标和临床疗效均优于对照组(P<0.05).结论:应用小剂量奥曲肽治疗肝硬化顽固性腹水,可显著改善患者的生化指标,提高临床疗效.

The Clinical Analysis of Low-dose Octreotide in Cirrhosis with Refractory Ascites

Objective: To evaluate efficacy of low-dose octreotide in cirrhosis with refractory ascites.Method: 90 liver cirrhosis with refractory ascites patients were selected in our hospital and divided into two groups,42 cases were control group with the routine treatment,48 cases were experimental group plus with octreotide.All patients with 1-2 months follow-up,compared two patients’ abdominal circumference,urine output,serum urea nitrogen,serum creatinine,serum albumin and clinical efficacy.Result: Compared of two groups,All biochemical indicators after treatment were better than before treatment(P<0.05),While the experimental group’s biochemical indicators and clinical efficacy were better than the control group(P<0.05).Conclusion: Low-dose octreotide treatment of liver cirrhosis with refractory ascites can significantly improve the patient’s biochemical parameters,and improve clinical efficacy.