精制血府胶囊治疗冠心病心绞痛的临床研究 |
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引用本文: | 汪晓芳,陈可远,王伟,史大卓,周佩云,陈可冀.精制血府胶囊治疗冠心病心绞痛的临床研究[J].中国中西医结合杂志,1998,18(7):399-401. |
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作者姓名: | 汪晓芳 陈可远 王伟 史大卓 周佩云 陈可冀 |
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作者单位: | 中国中医研究院西苑医院!北京100091 |
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基金项目: | 国家科委博士基金项目!(94 D 12 ) |
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摘 要: | 为观察精制血府胶囊对冠心病心绞痛的治疗作用。方法57例患者随机单盲分为 精制血府胶囊组与常规西药治疗组。结论:加用精制血府胶囊冠心病心绞痛比单用西药效果更好。
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关 键 词: | 精制血府胶囊 心绞痛 内皮素 降钙素 基因相关肽 |
Clinical Study of Purified Xuefu Capsule in Treating Angina Pectoris |
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Authors: | Wang Xiaofang Chen Keyuan Wang Wei Xiyuan Hospital China Academy of TCM Beijing |
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Abstract: | OBJECTIVE: To study the effect of purified Xuefu Capsule (PXFC) in treating angina pectoris (AP). METHODS: Fifty-seven patients with AP were randomly divided into two groups. Group A (30 cases) was treated with PXFC and western medicine, and group B(27 cases) with western medicine (isosorbide dinitrate, diltiazem or atenolol) alone. RESULTS: The total effective rates and ECG ST-T changes of AP were 93.3% and 63.3% respectively in group A. These results were all superior to those of group B (P < 0.05). Moreover, in group A the level of plasma endothelin (ET-1) decreased from 85.09 +/- 37.56 ng/L to 61.19 +/- 4.02 ng/L, and that of calcitonin gene related peptide (CGRP) increased from 58.64 +/- 19.30 ng/L to 88.87 +/- 20.41 ng/L. Comparing with group B, these changes were statistically different (P < 0.01). CONCLUSIONS: The effects of adding PXFC on conventional treatment with western medicine were better than those of western medicine. |
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Keywords: | purified Xuefu capsule angina pectoris endothelin calcitonin gene related peptide |
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