Thalamic and hypothalamic tumors of childhood: endocrine late effects |
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Authors: | Oberfield S E Garvin J H |
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Institution: | Division of Pediatric Endocrinology and Pediatric Oncology, Babies and Children's Hospital of New York, NY 10032, USA. seo8@columbia.edu |
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Abstract: | Children who have received chemotherapy and radiation therapy for treatment of thalamic/hypothalamic tumors are at risk for late effects, specifically endocrine dysfunction. Evaluation of growth and pubertal development, thyroid function and integrity of the hypothalamic-pituitary-adrenal axis should be undertaken in a prospective manner. Issues of metabolic disturbances such as obesity, altered body composition/bone density as well as ultimate fertility also need to be addressed by ongoing prospective evaluations. |
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