| 胃粘膜不同病变细胞核仁组成区嗜银蛋白的定量分析 |
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| 引用本文： | 法金枝 熊安宜 孙琪 宋京栓 刘建东. 胃粘膜不同病变细胞核仁组成区嗜银蛋白的定量分析[J]. 宁夏医科大学学报, 1994, 16(1): 21-23 |
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| 作者姓名： | 法金枝 熊安宜 孙琪 宋京栓 刘建东 |
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| 作者单位： | 宁夏人民医院病理科 |
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| 摘 要： | 应用核仁组成区嗜银蛋白(AgNORs)染色技术观测了100例胃良，恶性病变细胞AgNORs含量及形态。结果显示：慢性浅表性胃炎上皮细胞核内AgNORs计数平均为1．41；慢性萎缩性胃炎为1．55，慢性胃炎伴上皮不典型增生为2．59，胃癌为3．56，组间均数差异有统计学意义(P<0．01)。AgNORs形态分布各组间亦有明显差异。表明AgNORs可作为判断胃上皮细胞增生与分化程度的一项形态定量指标，AgNORs染色技术有助于胃癌及癌前病变的鉴别诊断。
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| 关 键 词： | 核仁组成区嗜银蛋白 胃癌 胃粘膜 不典型增生 恶性病变 形态定量 胃上皮细胞 NOR 显示 平均 |
QUANTITATIVE ANALYSIS OF AgNORs CONTENT IN DIFFERENT PATHOLOGICAL LESION OF GASTRIC MUCOSA |
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| Fa Jinzhi,Xiong Anyi,Sun Qi,Song jing shuan,Liu jiandong. QUANTITATIVE ANALYSIS OF AgNORs CONTENT IN DIFFERENT PATHOLOGICAL LESION OF GASTRIC MUCOSA[J]. Journal of Ningxia Medical College, 1994, 16(1): 21-23 |
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| Authors: | Fa Jinzhi Xiong Anyi Sun Qi Song jing shuan Liu jiandong |
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| Abstract: | AgNORs content of chronic gastritis,dysplasia and gastric carcinomawere analysed by using AgNORs stained technique.sections were stainedto show AgNORs dark particles.The results showed that the differencesof mean AgNORs content among the groups were of very marked statisti-cal significance(P<0.01)and the AgNORs morphological differences weresignificant as well.The results also suggested that quantitative analysisof AgNORs content could be used in distinguish the precancerous lesionfrom the gastric carcinoma. |
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| Keywords: | stomach neoplasms gastritis nucleolus organizer region quantitative analysis |
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