阜阳市人群HBV感染的血清流行病学调查

目的了解某地自然人群乙型肝炎病毒(HBV)感染情况。方法调查2005年3-12月在某疾病预防控制中心进行健康体检人群的HBV血清标志物检测结果。HBV血清标志物检测采用酶联免疫吸附试验。结果单纯检测乙型肝炎表面抗原(HBsAg)的2 802人中,阳性255人,阳性率9.10%;各年龄组人群以31~40岁组HBsAg阳性率最高,占12.16%(71/584)。1 907例检测HBV5项血清标志物者中,HBsAg阳性者238例(12.48%),以HBsAg阳性合并抗HBe、抗HBc阳性为主(44.96%),HBsAg阳性合并HBeAg、抗HBc阳性次之(38.24%);5项全阴性者占总人群的46.88%。结论该地区自然人群HBV感染水平较高,近一半人没有保护性抗体,应加强健康宣教,推广普及乙肝疫苗的接种,改善环境卫生。

Seroepidemiological investigation on hepatitis B viral infection in the population of Fuyang City

Objective To investigate hepatitis B viral(HBV) infection state among the natural population of a certain area.Methods Detection results of HBV serological markers in persons who received physical examination in a disease control and prevention center from March to December 2005 were investigated and analysed,HBV serological markers were detected with ELISA assay.Results Among 2 802 persons who only performed HBsAg detection,255 persons were positive,the positive rate was 9.10%;persons who was between 31~40 years old had the highest HBsAg positive rate,which was 12.16%(71/548).Among 1 907 persons who received five serological markers detection,238(12.48%) were positive,the majority were HBsAg positive associated with anti-HBe and anti-HBc(44.96%) positive,the next were HBsAg positive associated with HBeAg and anti-HBc(38.24%);46.88% persons were all negative in five serological marker detection.Conclusion The infection in HBV among natural population in this area is common,nearly half the population had no protective antibodies,health education should be strengthened,HBV vaccination should be popularized and environment hygiene should be improved.