Abstract: | The respiratory system was studied in 221 patients with chronic pyelonephritis (CP), satisfactory renal function and varying arterial pressure (AP) using tests of systemic hemodynamics, echocardiography, zonal rheography of the lungs and rheospirography. Ventilation-perfusion correlations were also taken into account. It is shown that the respiratory system, along with circulatory organs, is involved in the pathological process at early stages of pyelonephritic inflammation. Patients with the so-called "normal high AP" develop vascular dysfunction in the lungs manifesting in enlarged pulmonary artery base without an increase in pressure gradient in it, gradual growth of resistance of not only systemic vascular bed of the greater but lesser circulation as well, ventilation dysfunction of the lungs by the restrictive type, imbalance between the ventilatory reserve and reserve of pulmonary and systemic blood flow with progression of arterial hypertension. |