| 新型严重脓毒症治疗剂--重组人激活蛋白C |
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| 引用本文： | 纪立伟,谭玲,傅得兴. 新型严重脓毒症治疗剂--重组人激活蛋白C[J]. 中国新药杂志, 2005, 14(3): 360-362 |
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| 作者姓名： | 纪立伟 谭玲 傅得兴 |
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| 作者单位： | 卫生部北京医院药剂科,北京,100730 |
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| 摘 要： | 通过文献检索综述了用于治疗成人严重脓毒症的药物重组人激活蛋白C的药理作用、药代动力学及临床评价.在1690名患者参加的PROWESS临床试验中,它可以降低严重脓毒症患者28天治疗期内各种原因的死亡率且使用较安全.
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| 关 键 词： | 重组人激活蛋白C 药理作用 药代动力学 临床评价 |
| 文章编号： | 1003-3734(2005)03-0360-03 |
Recombinant human activated protein C,a new agent to treat the severe sepsis |
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| JI Li-wei,TAN Ling,FU De-xing. Recombinant human activated protein C,a new agent to treat the severe sepsis[J]. Chinese Journal of New Drugs, 2005, 14(3): 360-362 |
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| Authors: | JI Li-wei TAN Ling FU De-xing |
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| Abstract: | Recombinant human activated protein C is an intravascular fluid of a recombined human activated protein C. It is the first bioengineering agent adopted by FDA for treatment of severe sepsis in USA. Its pharmacological effects and clinical evaluation were reviewed in this article. |
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| Keywords: | recombinant human activated protein C pharmacological actions pharmacokinetics clinical evaluation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
