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药物性急性消化道粘膜损害
引用本文:霍继荣,吴小平,刘德良,凌奇荷. 药物性急性消化道粘膜损害[J]. 中国内镜杂志, 2002, 8(7): 37-38
作者姓名:霍继荣  吴小平  刘德良  凌奇荷
作者单位:中南大学湘雅二医院消化内科,长沙410011
摘    要:目的 :了解非甾体消炎药及某些抗生素引起消化道粘膜损害的情况。方法 :跟踪观察 1 1例服克林霉素、3例服泰诺、4例服感康后的消化道症状、内镜下消化道粘膜的改变及病理改变。结果 :药物性急性消化道粘膜损害主要表现为食管、胃、末端回肠粘膜糜烂、溃疡及出血。药物性消化道损害大多与个体对药物反应有关 ,也不排除与药物本身的毒副作用、酸碱度及抗原性有关。结论 :对药物引起的消化道粘膜损害 ,要尽早发现 ,立即停药 ,并注意预防。

关 键 词:药物  消化道  粘膜损害
修稿时间:2002-01-02

DRUG- INDUCED ACUTE DIGESTIVE TRACT MUCOSA INJURY
Huo Jirong,Wu Xiaoping,Liu Deliang,et al.. DRUG- INDUCED ACUTE DIGESTIVE TRACT MUCOSA INJURY[J]. China Journal of Endoscopy, 2002, 8(7): 37-38
Authors:Huo Jirong  Wu Xiaoping  Liu Deliang  et al.
Affiliation:Huo Jirong,Wu Xiaoping,Liu Deliang,et al. Digestive Department,Second Xiangya Hospital,Central South University,Changsha 410011
Abstract:Objective:To assess the injury induced by drugs on digestive tract mucosa. Methods:To observe the digestive symptoms and pathological changes of digestive tract mucosa of the patients after taking the drug Clindamycin in 11 cases,Tylnend in 3 and Gangkang in 4 cases.Results:The drug-induced injury was considered to be mostly related to the individual reaction to drugs.However the toxicity, purity, acidity and antigenicity of drags were related as well.Conclusion:Early diagnosis and prompt withdrawal of medication were important to prevent the drug-induced injury.
Keywords:Drug  Digestive Tract  Mucosa Injury
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