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Adsorption of antineoplastic drugs to polyalkylcyanoacrylate nanoparticles and their release in calf serum |
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| Authors: | P Couvreur B Kante M Roland P Speiser |
| Abstract: | Conditions are described for attaching anticancer drugs to polyalkylcyanoacrylate nanoparticles, a new drug delivery system for cells that exhibit endocytic uptake. They are ultrafine, metabolizable, and able to associate with various drugs in a nonspecific manner. Data are given for the in vitro degradation and for drug release from this new drug carrier system. |
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