脉冲电场用于心律失常消融的研究进展

脉冲电场消融是一种很有前景的治疗心律失常的新型非热消融技术,依靠不可逆电穿孔机制造成组织破坏.心肌容易受到不可逆的损伤,而食管、膈神经、肺静脉和冠状动脉则相对不易受到损伤.因其具有的组织特异性和非热消融等优点,在心律失常的消融治疗,特别是在心房颤动肺静脉隔离过程中,显示它是一种非常有吸引力的能源.

Pulsed Electric Field for Ablation of Arrhythmia

Pulsed field ablation is a promising new non-thermal ablation technique for the treatment of arrhythmia,which relies on irreversible electroporation mechanism to cause tissue destruction.The myocardium is vulnerable to irreversible damage,while the esophagus,phrenic nerve,pulmonary veins and coronary arteries are relatively immune.Due to its advantages of tissue specificity and non-thermal ablation,it has been shown to be a very attractive energy source in the ablative treatment of arrhythmia,especially in the process of pulmonary vein isolation in atrial fibrillation.