| 硫化氢对糖尿病心肌病的保护作用 |
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| 引用本文： | 武韧,常贵全,孙凤起,李鸿珠. 硫化氢对糖尿病心肌病的保护作用[J]. 心血管病学进展, 2021, 0(1): 52-55 |
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| 作者姓名： | 武韧 常贵全 孙凤起 李鸿珠 |
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| 作者单位： | 哈尔滨医科大学基础医学院/病理生理学教研室 |
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| 基金项目： | 国家自然科学基金(81770486)。 |
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| 摘 要： | 糖尿病心肌病是指发生于糖尿病患者,不能用高血压性心脏病、冠状动脉粥样硬化性心脏病及其他心脏病变来解释的一种特异性心肌病.研究表明,硫化氢作为内源性气体信号分子,对糖尿病心肌病心脏具有保护作用,其机制主要与减轻炎症反应,减轻氧化应激损伤,抑制心肌细胞凋亡,促进自噬有关.
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| 关 键 词： | 硫化氢 糖尿病心肌病 心肌细胞 |
Protective Effect of Hydrogen Sulfide in Diabetic Cardiomyopathy |
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| WU Ren,CHANG Guiquan,SUN Fengqi,LI Hongzhu. Protective Effect of Hydrogen Sulfide in Diabetic Cardiomyopathy[J]. Advances in Cardiovascular Diseases, 2021, 0(1): 52-55 |
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| Authors: | WU Ren CHANG Guiquan SUN Fengqi LI Hongzhu |
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| Affiliation: | (Department of Pathophysiology/School of Basic Medicine,Harbin Medical University,Harbin 150086,Heilongjiang,China) |
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| Abstract: | Diabetic cardiomyopathy is a specific cardiomyopathy that occurs in diabetic patients and can not be explained by hypertensive heart disease,arteriosclerosis,or other heart conditions.Studies have shown that hydrogen sulfide,as an endogenous gas signaling molecule,has a protective effect on heart of diabetic cardiomyopathy patients,and its mechanism is mainly related to reducing inflammation,reducing oxidative stress,inhibiting cardiomyocytes apoptosis,and promoting autophagy. |
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| Keywords: | Hydrogen sulfide Diabetic cardiomyopathy Cardiomyocytes |
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