| 复方替硝唑栓的研制与临床应用 |
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| 引用本文： | 何笑蓉,翟建军,闫小燕. 复方替硝唑栓的研制与临床应用[J]. 中国药学杂志, 1999, 0(9): 598-600 |
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| 作者姓名： | 何笑蓉 翟建军 闫小燕 |
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| 作者单位： | 卫生部北京医院药剂科(何笑蓉!北京市100730，闫小燕!北京市100730，房建和!北京市100730，孙春华!北京市100730，宋友华!北京市100730)，卫生部北京医院妇科(翟建军!北京市100730)，卫生部北京医院检验科(陈东科!北京市100730) |
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| 摘 要： | 目的:增加替硝唑临床应用的剂型,满足妇科治疗滴虫性阴道炎和细菌性阴道炎的需要。方法:采用半合成脂肪酸甘油酯为基质,以替硝唑和氧氟沙星为主药,按照制备栓剂的一般方法制备复方替硝唑栓。结果:所得制剂疗效确切,无刺激性,且质量可控。结论:复方替硝唑栓是值得临床推广的制剂。
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| 关 键 词： | 复方替硝唑栓 制备 临床应用 |
| 收稿时间： | 1998-10-07; |
Preparation and clinical application of compound tinidazole suppository |
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| He Xiaorong. Preparation and clinical application of compound tinidazole suppository[J]. Chinese Pharmaceutical Journal, 1999, 0(9): 598-600 |
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| Authors: | He Xiaorong |
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| Affiliation: | (He XR)，Zai Jianjun (Zai JJ)，Yan Xiaoyan (YanXY)，et a |
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| Abstract: | OBJECTIVE:To extend clinical application of preparations of tinidazole,and satisfy the needs of gynecologic treating trichomonas vaginitis and bacterial vaginitis.METHODS:Semi synthetic glyceryl stearate is used as exipinet.The main ingredient of suppository contains tinidazole and ofloxacin.The suppository is prepared according to the ordinary method of mannufacturing.RESULTS:The effect of suppository is good and no stimulution to mucosa.Its quality can be controlled.CONCLUSION:It is worth expanding in the clinic. |
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| Keywords: | compound tinidazole suppository preparation clinical application |
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