Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks |
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| Authors: | JP OPDEBEECK JYM WONG LA JACKSON C DOBSON |
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| Institution: | Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia. |
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| Abstract: | Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination. |
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| Keywords: | Boophilus microplus tick cattle protection vaccines immunity membrane-associated and soluble gut antigens |
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