| Abstract: | Pieces of the parietal bone of inbred C57BL/Mib mice aged 3 days were grown in culture for 3 days. The following substances were added to the culture medium: 0.01 unit/ml (series I) and 0.1 unit/ml (series II) parathormone, 0.1 unit/ml (series III) and 1 unit/ml (series IV) heparin, and 0.01 unit/ml parathormone +0.1 unit/ml heparin (series V). Resorption of bone tissue of the explants was observed in the experiments of series II and V, but not in those of series I, III, and IV. Parathormone (0.01 unit/ml), combined with heparin (0.1 unit/ml), stimulated resorption of the bone tissue of the explant (series V), whereas if added separately in the same dose it had no such action.Laboratory of Experimental Genetics, Institute of Medical Genetics, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 9, pp. 97–99, September, 1975. |
