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Physostigmine for the acute treatment of restless legs syndrome
Authors:Alpert Calvert C  Tobin D Patrick  Dierdorf Stephen F
Affiliation:Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, 165 Ashley Avenue, Suite 525, PO Box 250912, Charleston, SC 29425, USA. dierdorf@musc.edu
Abstract:We present a case report of an acute episode of restless legs syndrome that interfered with the performance of a diagnostic imaging procedure of the cervical spine. The patient had a 19-yr history of restless leg syndrome with periodic limb movements during sleep. Treatment with additional sedation and opioids did not alleviate the leg movements. IV administration of 1 mg of physostigmine eradicated all extraneous leg motion.
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