过敏性紫癜的特殊表现

目的：观察过敏性紫癜的心脏、肺和中枢神经系统损害的发生率及临床特点。方法：对104例过敏性紫癜患者在诊断同时行心肌酶谱、心电图、胸片和脑电图检查，根据相应表现进一步行超声心动图、胸部和头部CT及脑脊液等检查。结果：104例过敏性紫癜患者中有18例（17．3％）并发心脏受损，主要表现为各种类型心电图改变，心肌酶谱增高及心包积液。11例（13．4％）有脑电图异常，其中9例有神经系统受损的症状或体征。2例胸片检查诊断为弥漫性间质性肺炎。所有病例应用肾上腺皮质激素治疗后均治愈。结论：过敏性紫癜合并心脏和神经系统损害是临床较常见的表现，早期识别并及时应用激素治疗及对症处理可避免严重并发症的发生，提高治疗效果。

Cardiopulmonary and neurologic involvement of Henoch-Schonlein purpura

Objective To investigate the incidence and clinical characteristics of cardiopulmonary and neurological involvement in patients with Henoch-Schonlein purpura.Methods One hundred and four patients with Henoch-Schonlein purpura were studied.Blood samples for the determination of serum cardiac muscle enzyme were drawn.Examination of electrocardiogram,electroencephalogram and chest X-ray were performed at diagnosis.Results Of 104 cases,18 patients(17.3%) presented with cardiac involvement.The patients with cardiac involvement were characterized by abnormal electrocardiogram and increasement of cardiac muscle enzyme.The electroencephalogram was abnormal in 13.4%(11/82) Henoch-Schonlein purpura patients.These cardiac manifestations were usually mild and transient and were successfully treated with steroids.Conclusion Cardiac involvement was common in patients with Henoch-Schonlein purpura.Early recognition of myocardial injury,myocardial support and early steroid therapy might improve outcome and prevent fatal complications.