中西药联合治疗泌尿生殖道支原体感染的疗效观察

目的:探讨中西药联合治疗泌尿生殖道支原体感染的临床疗效及疗程结束后2年内的复发情况。方法:选取2016–2018年河南科技大学第一附属医院皮肤性病科、妇科、泌尿外科收治的248例患者,随机分为两组,各124例。观察组患者采用敏感抗菌药物结合中药施治;对照组患者采用敏感抗菌药物治疗。2周后进行疗效比较,并对疗程结束后2年内的患者进行复查。结果:观察组患者的痊愈率为90.3%高于对照组的72.6%,差异具有统计学意义(P<0.01);两组患者在治疗和观察过程中,均未出现明显的不良反应;治疗后,观察组患者的单纯解脲支原体(UU)感染的转阴率为92.5%高于对照组的73.7%,观察组患者的单纯人型支原体(MH)感染的转阴率为87.5%高于对照组的68.8%,观察组患者的MH+UU混合感染的转阴率为83.3.0%高于对照组的75.0%,差异均具有统计学意义(P<0.01);观察组患者2年的复发率为6.5%低于对照组的22.6%,差异均具有统计学意义(P<0.05)。结论:中西药联合治疗泌尿生殖道支原体感染比单用西药好。

Observation on Curative Effect of Combined Chinese and Western Medicine on Mycoplasma Infection of Urogenital Tract

Objective To explore the clinical efficacy of combined Chinese and Western medicine in the treatment of mycoplasma infection in urogenital tract and the recurrence situation within two years after the end of the course of treatment.Methods 248 patients were divided into the treatment group(124 patients)and the control group(124 patients).The treatment group was received sensitive antibiotic and traditional Chinese medicine based on differentiation of symptoms and signs.The control group was only received sensitive antibiotic every day for two weeks.And then recheck the recurrence after the course of treatment two years later.Results The cure rate of the observation group was 90.3%higher than that of the control group 72.6%,the difference was statistically significant(P<0.01).During the treatment and observation of the two groups of patients,no obvious adverse reactions occurred;after treatment,the negative rate of UU infection in observation group was 92.5%higher than 73.7%in control group.The negative rate of simple Mycoplasma hominis(MH)infection in the observation group was 87.5%higher than that in the control group was 68.8%.The negative rate of MH+UU mixed infection in the observation group was 83.3.0%higher than that of the control group 75.0%,and the difference was statistically significant(P<0.01).The two-year recurrence rate of the observation group was 6.5%lower than that of the control group 22.6%,and the difference was statistically significant(P<0.05).Conclusion Combined treatment by traditional Chinese and Western medicine for mycoplasma infected in genitourinary tract was better than single Western medicine.