| Abstract: | Abstract: The 24 hour LD50 dose for intraperitoneally injected sodium fluoride was determined in developing and young adult rats of both sexes. The developing animals tolerated two and a half times as much fluoride as the young adults when expressed as mg FVkg of body weight. There were no significant differences between the two sexes. The 24 hour LD50 values were: 4 day old females 45 (39–52), males 40 (34–48); 20 day old females 47 (39–57), males 51 (47–55); 60 day old females 30 (21–43), males 28 (17–42); 90 day old females 21 (17–26), males 20 (17–24) mg F-/kg of body weight. |
