| 血栓形成倾向与子痫前期 |
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| 引用本文： | 张焱,胡娅莉. 血栓形成倾向与子痫前期[J]. 中国妇幼健康研究, 2007, 18(2): 131-134 |
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| 作者姓名： | 张焱 胡娅莉 |
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| 作者单位： | 南京大学医学院附属鼓楼医院妇产科,江苏,南京,210008 |
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| 摘 要： | 子痫前期的发病原因不明,关于血栓形成倾向在子痫前期的发病机制中所起的作用是有争议的.子痫前期患者胎盘局部存在着比正常妊娠广泛的多的微血栓,这表明与血栓形成倾向有关的胎盘微血栓形成和胎盘功能不全与重度子痫前期的发病有一定的因果关系.该文主要对不同类型的子痫前期与血栓形成倾向、抗凝治疗和妊娠结局的研究进展加以综述.
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| 关 键 词： | 子痫前期 血栓形成倾向 围产结局 抗凝治疗 |
| 文章编号： | 1673-5293（2007）02-0131-04 |
| 收稿时间： | 2007-01-27 |
| 修稿时间： | 2007-01-27 |
Thrombophilia and preeclampsia |
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| ZHANG Yan,HU Ya-li. Thrombophilia and preeclampsia[J]. Chinese Journal of Maternal and Child Health Research, 2007, 18(2): 131-134 |
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| Authors: | ZHANG Yan HU Ya-li |
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| Affiliation: | Department of Gynecology and Obstetrics, The Affiliated Drum Tower Hospital of Medical College, Nanjing University, Jiangsu Nanjing 210008, China |
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| Abstract: | The etiology of preeclampsia remains unknown. The role of thrombophilia in pathogenesis of preeclampsia is controversial. Extensive and severe placental microinfarcts and microthrombosis were observed in those women with preeclampsia, suggesting a cause-andeffect relationship between placental microthrombosis associated with thrombophilias, placental dysfunction and severe preeclampsia. The article reviewed progress in research on relationship between thrombophiha and varied types of preeclampsia, anticoagulant therapy and pregnancy outcomes and so on. |
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| Keywords: | preeclampsia thrombophilia pregnancy outcome anticoagulant therapy |
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