赖诺普利对136例高血压病肾功能的影响

目的:观察探讨赖诺普利对136例高血压病肾功能的影响。方法:选择2009年2月—2011年2月高血压病患者136例为观察组,另选同期指数相近的高血压患者120例为对照组。对观察组患者进行口服赖诺普利治疗18mg/d,对照组患者接受口服缬沙坦治疗90mg/d。观察两组患者血压变化,以及24h尿蛋白、胆固醇、血肌酐、血尿素氮和不良反应的比较。结果:经4～6周治疗后,接受口服赖诺普利治疗患者总有效率为75.9%,接受口服缬沙坦治疗患者总有效率为70.6%。结论:赖诺普利可使尿蛋白含量减少,平稳有效抗压,使高血压病肾功能得到改善,临床应用安全、有效。

Lisinopril on 136 Cases with Hypertension the Effect of Renal Function

Objective： To explore the impact of lisinopril on renal function of 136 cases ofhypertension. Methods. This article chooses since 2009 to July 2011 02 feb, 136 cases,aged 58 years old -73 years ,with female 57 patients, male 79 cases of the observation group chose the same period 120 cases with high blood pressure similar index, age 56 years old-71 years, with female 51 cases, male 69 cases of control group. The observation group of patients with oral lisinopril 18 mg/d, patients receiving oral losartan treat ment 90 mg/d. Watch two groups were blood pressure changes, and 24 h urine protein, cholesterol, blood serum creatinine, blood urea nitrogen and adverse reaction of the comparison. Results ： After four to six weeks after the treatment, receiving oral lisinopril patients the total effective rate was 75.9 % , receiving oral losartan treat patients with the total effective rate was 70.6 %. Conclu- sion：Lisinopril can make the urine proteincontent, thesmoothandefficient compression, hypertension renalfunction improved, safe and effective.