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正交试验优选复方丹参软胶囊提取工艺
引用本文:黄舒丽,杨玳.正交试验优选复方丹参软胶囊提取工艺[J].亚太传统医药,2012,8(3):33-34.
作者姓名:黄舒丽  杨玳
作者单位:黄舒丽 (广东仙乐制药有限公司,广东汕头,515041) ; 杨玳 (广东仙乐制药有限公司,广东汕头,515041) ;
摘    要:目的:优选复方丹参软胶囊的最佳提取工艺。方法:以浸膏得率和丹参素含量为指标,用高效液相色谱测定,采用L9(34)正交试验法优选提取工艺。结果:最佳提取工艺条件为每次加水10倍,煎煮3次,1.5h/次。结论:优选的复方丹参软胶囊提取工艺稳定、可行,提取率高。

关 键 词:复方丹参软胶囊  正交试验  提取工艺  丹参素

Study on Optimizing the Decocting Extraction of Compound Salvia Softgel by Orthogonal Design Method
Huang Shuli Yang Dai.Study on Optimizing the Decocting Extraction of Compound Salvia Softgel by Orthogonal Design Method[J].Asia-Pacific Traditional Medicine,2012,8(3):33-34.
Authors:Huang Shuli Yang Dai
Institution:Huang Shuli Yang Dai(Sirio Pharma Co.,Ltd,Guangdong 515041,China)
Abstract:Objective:To study on optimizing decocting extraction for Compound Salvia Softgel by orthogonal design method.Methods:To optimize the decocting extraction with L9(34) orthogonal test,the yields of extracts,the content of the danshensu were used as evaluating criteria,They was determined by HPLC.Results:The optimal condition was 10 folds amount of water,3 times,1.5 hours each time.Conclusion:The optimized extractive technology is stable and efficient with high yields.
Keywords:Compound Salvia Softgel  Orthogonal Test  Extraction Technology  Danshensu
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