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Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo
Authors:Schattenberg Jörn M  Zimmermann Tim  Wörns Marcus  Sprinzl Martin F  Kreft Andreas  Kohl Tobias  Nagel Michael  Siebler Jürgen  Bergkamen Henning Schulze  He You-Wen  Galle Peter R  Schuchmann Marcus
Affiliation:1 Department of Medicine, University Medical Center, Johannes Gutenberg University, 55101 Mainz, Germany
2 Department of Pathology, University Medical Center of the Johannes Gutenberg University, 55101 Mainz, Germany
3 Department of Medicine, University of Erlangen, Germany
4 German National Cancer Center, Heidelberg, Germany
5 Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA
Abstract:
Keywords:c-FLIP   CD95     smallcaps"  >d-Galactosamine/LPS   Concanavalin A   JNK   Bid   Apoptosis   Caspase-8   Liver injury   Cell death
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