通心调脂胶囊对冠心病合并高脂血症患者血脂和血液流变学的影响

目的研究通心调脂胶囊对冠心病合并高脂血症患者血脂和血液流变学的影响。方法将80例冠心病合并高脂血症患者随机分为治疗组（40例）和对照组（40例），对两组血脂和血液流变学指标进行比较。结果治疗组血脂总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL-C）明显降低，高密度脂蛋白（HDL—C）明显升高；血液流变学全血黏度高切变率（ηbH）、全血黏度低切变率（ηbL）、血浆比黏度（ηp）、血细胞比容（HCT）、纤维蛋白原（Fib）明显降低。与对照组比较有显著性差异（P〈0．05或P〈0．01）。结论通心调脂胶囊可明显改善冠心病合并高脂血症患者血脂和血液流变学指标，是治疗冠心病合并高脂血症患者的有效药物。

Impact of Tongxin Tiaozhi Capsules on Blood Lipid and Hemorheology in Patients with Coronary Heart Disease and Hyperlipidemia

Objective To research the impact of Tongxin Tiaozhi Capsules on blood lipid and hemorheology in patients with coronary heart disease（CHD） and hyperlipidemia. Methods 80 cases of CHD and hyperlipidemia were randomized into treatment group （40 cases ）and control group（40 cases）. The indexes of blood lipid and hemorheology were compared between two groups. Results In treatment group, the levels of TC, TG and LDL- C decreased apparently and HDL- C increased apparently; the levels of ηbH, ηbL, ηp, ηh, HCT and Fib in hemorheology decreased apparently. The significant difference presented in comparison with control group（P 〈 0.05 or P 〈 0. 01 ）. Conclusion Tongxin Tiaozhi Capsules improve the indexes of blood lipid and hemorheology in the patients with CHD and hyperlipidemia and are effective in treatment of CHD and hyperlipedmia.