433株不动杆菌的临床分布与耐药性分析

目的：探讨我院分离的不动杆菌的感染分布及耐药情况。方法：收集临床标本分离的不动杆菌，细菌鉴定及药敏试验采用BDPhoenix全自动微生物鉴定药敏系统。结果：360株（83．1％）不动杆菌来自于痰标本。47株来自于伤13分泌物（10．9％）。临床分布以呼吸内科为主（32．6％），其次为重症监护室和新生儿病房，均占12．9％。14种抗菌药物中，鲍曼不动杆菌对多黏菌素耐药率较低（0．78％）。对亚胺培南和美罗培南的耐药率分别为6．01％和1．57％。洛菲不动杆菌对多种药物的耐药率低于鲍曼不动杆菌。结论：不动杆菌主要来自于痰和呼吸内科，耐药率较高，应加强不动杆菌的耐药性检测，选择合理的抗生素。

Distribution and drug resistance of 433 clinical acinetobacter strains

Objective ：To investigate the distribution and drug resistance of clinical acinetobacter strains in our hospital. Methods： Drug resistance of aeinetobaeter strains from Jan. 2008 to Dec. 2008 were analyzed. The strains were identified and drug susceptibility was tested by BD Phoenix automated microbiology system. Results：360 strains were isolated from sputum. 32.6% acinetobacter strains were from respiratory department, followed by the intensive care unit and the neonatal department （12.9%）. The drug resistance of acinetobacter baumannii to colistin ,impenem,meropenem was 0.78% ,6.01% and 1.57% respectively. Aeinetobacter lwoffi was more sensitive to some antimierobial agents than Acinetobaeter baumannii. Conclusion：Clinical aeinetobacter mainly comes from the sputum and respi- ratory department.The resistant rate is high. We should enhance the surveillance of antimicrobial resistance and choose proper antimicrobial agents.