Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma |
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| Authors: | B Rohrmoser D K Lüdecke P C Scriba |
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| Institution: | (1) Klinik für Innere Medizin Medizinische Hochschule Lübeck, Germany;(2) Neurochirurgische Abteilung Universitätskrankenhaus Hamburg, Germany |
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| Abstract: | Summary Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica. Despite these findings, the diagnosis of pituitary was confirmed Cushing's syndrome by computerized tomography and a transphenoidal operation.Abbreviations CRF
corticotropin releasing factor
- CD
Cushing's disease
- CS
Cushing's syndrome
- CT
computerized tomography
- GH
growth hormone
- FSH
follicle-stimulating hormone
- LH
luteinizing hormone
- LH-RH
luteinizing hormone releasing hormone |
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| Keywords: | Corticotropin-releasing factor (CRF) Cushing's disease ACTH |
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