关注黄斑区肥厚型脉络膜疾病谱的概念及研究

肥厚型脉络膜疾病谱是近年来随着眼科诊疗技术的进步而提出的新概念.眼底影像学诊断技术的巨大进步,特别是扫频源OCT在扫描速度、深度、扫描模式以及扫描软件方面的突破,克服了以往眼底成像技术的局限性,使得深达脉络膜,甚至巩膜的结构得以清晰成像,为视网膜脉络膜疾病的诊断、分型及发病机制研究提供了有用信息和依据.近年来正是基于OCT对脉络膜越来越精细的成像特点提出了肥厚型脉络膜疾病谱的概念,国外学者将与慢性持续性脉络膜增厚相关的具有临床表型及发病机制相似的黄斑疾病进行归类并加以病名,为该类疾病的临床诊疗及临床研究提供了新的方向.眼科医师应该关注这些新的进展和相关的研究工作.本文就其概念、发病机制、临床表型做一简要评述.

Paying attention to the concept and research of pachychoroid disease spectrum

Pachychoroid disease spectrum is a novel concept in ophthalmology upon the development of ocular diagnosis and treatment.Recent breakthroughs and advancements in OCT imaging technology such as enhanceddepth imaging spectral-domain OCT (EDI-OCT) and swept source OCT (SS-OCT) have led to improvements in scanning speed,depth,scanning mode and software.This allows better and more detailed visualization of more posterior and deeper structures such as choroid or sclera.The newly developed EDI-OCT and SS-OCT provide a new basis for the diagnosis and classification of the retinal choroidal diseases.Pachychoroid disease spectrum,a group of chronic persistent choroidal thickening associated with a similar clinical phenotype and pathogenesis of disease were named recently based on higher spatial resolution and more detailed choroidal imaging captured by EDI-OCT or SS-OCT.Ophthalmologists should pay more attentions to this new concept and its relative information.In this paper,the concept,pathogenesis,and phenotype of pachychoroid disease spectrum are emphasized.