雌激素与糖尿病性视网膜病变的研究进展

糖尿病性视网膜病变(diabetic retinopathy,DR)是糖尿病所有微血管病变中最严重且常见的致盲性眼部并发症.DR发病机制至今尚未完全明确,其发生与多种因素相关,存在多种学说.近年来DR的发生与性别、激素水平的关系成为眼科研究的热点,研究发现绝经后女性DR患病率明显增加,其中雌激素变化起着主要作用.了解雌激素与DR之间的关系将有助于DR的临床诊疗.本文就雌激素与DR的研究进展作一综述.

Recent advances in estrogen and diabetic retinopathy

Diabetic retinopathy (DR) is the most serious and common blinding ocular complication in all microangiopathy of diabetes mellitus.The occurrence of DR associated with a variety of factom,the pathogenesis has not yet been completely clear,and there are several theories.In recent years,the relationship between the occurrence of DR and sex hormone levels become a hot ophthalmic research,research shows that the prevalence of DR significantly increased in postmenopausal women,in which estrogen change plays the main role.Learning connection between estrogen and DR will contribute to the clinical diagnosis and treatment of DR.This article reviews recent research advances in the relationship between estrogen and DR.