| 肿瘤干细胞在眼部恶性肿瘤中的作用 |
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| 引用本文： | 郑磊,温佳敏,张国明. 肿瘤干细胞在眼部恶性肿瘤中的作用[J]. 眼科新进展, 2017, 0(7): 692-696. DOI: 10.13389/j.cnki.rao.2017.0176 |
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| 作者姓名： | 郑磊 温佳敏 张国明 |
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| 作者单位： | 1. 深圳市眼科医院,广东省深圳市,518040;2. 510000广东省广州市,眼科学国家重点实验室,中山大学中山眼科中心 |
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| 基金项目： | 深圳市国际合作项目(编号:GJHZ20160229170623135).Shenzhen International Cooperation Project (GJHZ20160229170623135) |
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| 摘 要： | 肿瘤干细胞是肿瘤组织中一小部分具有无限增殖和多向分化潜能的细胞群,在维持肿瘤的恶性增殖、耐药、复发和转移等方面起着决定性作用 眼部恶性肿瘤大多具有高复发、易转移和预后差等特点近年来研究发现眼部恶性肿瘤中存在肿瘤干细胞,可能与肿瘤的发生和发展密切相关.本文对肿瘤干细胞在眼部恶性肿瘤中作用的研究进展进行综述.
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| 关 键 词： | 肿瘤干细胞 眼部恶性肿瘤 转移 复发 |
Research progress on cancer stem cells in ocular malignancy |
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| ZHENG Lei,WEN Jia-Min,Zhang Guo-Ming. Research progress on cancer stem cells in ocular malignancy[J]. Recent Advances in Ophthalmology, 2017, 0(7): 692-696. DOI: 10.13389/j.cnki.rao.2017.0176 |
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| Authors: | ZHENG Lei WEN Jia-Min Zhang Guo-Ming |
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| Abstract: | Cancer stem cells (CSCs) are a small subset of cancer cells in the tumor,which possess the exclusive ability to proliferate indefmitely and multiple differentiation.These tumor cells play a crucial role in the maintenance of malignant proliferation,drug resistance,metastasis and recurrence.Majority of ocular malignancies have the properties of high recurrence,metastasis and poor prognosis.Recently,CSCs was found to exist in the ocular malignancies,also might be involved in the tumor initiation and progression.This article reviews the research progress on CSCs in ocular malignancy. |
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| Keywords: | cancer stem cells ocular malignancy metastasis recurrence |
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