Transient P300 abnormality of event-related potentials following unilateral temporal lobectomy |
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| Authors: | YOSHIO HIRAYASU MD HIROKAZU OHTA MD KOZO FUKAO MD CHIKARA OGURA MD JIRO MUKAWA MD |
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| Affiliation: | Departments of Neuropsychiatry and Faculty of Medicine, University of the Ryukyus, Okinawa, Japan;Departments of Neurosurgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan |
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| Abstract: | Abstract Event-related potentials (ERP) were recorded during auditory oddball tasks for a patient prior to and soon after left anterior temporal lobectomy. The N100 amplitude decreased bilaterally although the latency did not change after the lobectomy. The P300 amplitude decreased in the left hemisphere at 1 and 2 weeks after surgery, then recovered to the pre-operative level at 4 weeks. These findings suggest that the medial temporal structure participates in the generating system of P300. |
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| Keywords: | event-related potentials generator lobectomy N100 P300. |
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