慢性酒精中毒性精神障碍患者周围神经系统临床电生理研究

目的:探讨慢性酒精中毒性精神障碍患者周围神经系统的电生理改变。方法:对178例慢性酒精中毒性精神障碍患者进行电生理检查,观察肌电图(EMG)、运动神经传导速度(MCV)和感觉传导速度(SCV)的变化情况。结果:178例患者电生理检查结果提示有神经源性损害,上下肢EMG异常差异无显著性(P>0.05),SCV和MCV较对照组均有不同程度的减慢,而SCV的改变更加明显;SCV异常率为81.83%,且异常程度与饮酒年限呈正相关(P<0.05);28例双上肢无临床症状的患者中,12例尺神经MCV、SCV有改变。结论:慢性酒精中毒性精神障碍患者的周围神经有神经源性损害。

A CLINICAL AND ELECTROPHYSIOLOGICAL STUDY ON PERIPHERAL NERVOUS SYSTEM OF PATIENTS WITH MENTAL DISORDER ATTRIBUTED TO CHRONIC ALCOHOLISM

Objective:To explore the electrophysiological change of peripheral nervous system of patients with mental disorder attributed to chronic alcoholism.Methods:Through electrophysiological examination into 178 patients who suffered from chronic alcoholism,we observed the changes of their electromyogram (EMG),motorius conduction velocity (MCV) and sense conduction velocity (SCV).Results:The electrophysiological examination of the 178 patients indicated that their neurons were harmed.There were no obvious differences in EMG between upper and lower limbs (P>0 05).In comparison with the control group,SCV and MCV slowed down in some degree,and the change of SCV was more evident;the rate of abnormity was 81 83%,and the degree of abnormity was proportional to the length of drinking history (P<0.05);among the 28 patients whose upper limbs had no clinical symptoms,there were 10 patients whose MCV and SCV of the ulnar nerves had some changes.Conclusion:The peripheral nervous system of patients with mental disorder attributed to chronic alcoholism is harmed in neurons.