Chronic pancreatitis: A diagnostic dilemma |
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Authors: | Sinead N Duggan Hazel M Ní Chonchubhair Oladapo Lawal Donal B O’Connor Kevin C Conlon |
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Institution: | Sinead N Duggan;Hazel M Ní Chonchubhair;Oladapo Lawal;Donal B O’Connor;Kevin C Conlon;Professorial Surgical Unit, Department of Surgery, Trinity College Dublin, Centre for Pancreatico-Biliary Diseases, Trinity Centre for Health Sciences, Tallaght Hospital; |
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Abstract: | Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with 90% destruction of the gland. |
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Keywords: | Pancreatitis chronic Diagnosis Exocrine pancreatic insufficiency Pancreatic enzyme replacement therapy Malabsorption |
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