| 正常人不同年龄段脑海马区~1H-MRS变化的临床研究 |
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| 引用本文： | 马晓臣,王桂芝,王元春,程凯亮.正常人不同年龄段脑海马区~1H-MRS变化的临床研究[J].现代中西医结合杂志,2010,19(16):1965-1966. |
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| 作者姓名： | 马晓臣 王桂芝 王元春 程凯亮 |
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| 作者单位： | 吉林大学中日联谊医院,吉林,长春,130033 |
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| 基金项目： | 吉林市科委计划项目资助课题 |
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| 摘 要： | 目的通过比较不同年龄段正常人海马区磁共振质子波谱(1H-MRS)的差异,探讨正常人群随年龄增长其脑代谢功能的变化。方法采用1.5TMR I对60例正常人进行1H-MRS检查,检测双侧海马N-乙酰天门冬氨酸复合物(NAA)、胆碱复合物(Cho)与肌酸(Cr)的比值。结果青年组和中年组相比脑海马的NAA/Cr和Cho/Cr比值无明显改变,但青年组与老年组及中年组与老年组相比脑海马的NAA/Cr、Cho/Cr比值有明显的差异。结论正常人随年龄的增长可能会出现双侧海马区功能紊乱,从而导致脑部功能退化1。H-MRS可以为正常人随年龄改变所导致的海马区脑代谢物的变化提供一种有效的检测手段。
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| 关 键 词： | 健康人 磁共振波谱 海马 脑功能 |
Clinical study on change of ~1H-MRS in hippocampus of normal people of different ages |
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| Ma Xiaochen,Wang Guizhi,Wang Yuanchun,Cheng Kailiang.Clinical study on change of ~1H-MRS in hippocampus of normal people of different ages[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2010,19(16):1965-1966. |
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| Authors: | Ma Xiaochen Wang Guizhi Wang Yuanchun Cheng Kailiang |
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| Institution: | Ma Xiaochen,Wang Guizhi,Wang Yuanchun,Cheng Kailiang(China-Japan Union Hospital,Changchun 130033,Jilin,China) |
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| Abstract: | Objective It is to compare the differences in wave spectrum of proton magnetic resonance spectroscopy(1H-MRS) in hippocampus among normal people of different ages to explore the changes of their brain function.Methods 1H-MRS of 60 cases of normal people were detected by 1.5T MRI and relative values of NAA/Cr and Cho/Cr in both hippocampuses were detected.Results There was no significant difference in ratios of NAA/Cr and Cho/Cr between young group and middle-aged group,but there were significant differences... |
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| Keywords: | normal people magnetic resonance spectroscopy hippocampus brain function |
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